Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086271 | 0.77 | TSHR (0.50) | KMT2ATDP1HTR6ALDH1A1MEN1 | |
| SCHEMBL11211293 | 0.75 | APOBEC3G (0.58) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| SCHEMBL26413509 | 0.75 | APOBEC3G (0.58) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| SCHEMBL182738 | 0.75 | LMNA (0.67) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| Water SCHEMBL28154432 | 0.73 | LMNA (0.64) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| Hydrochloric Acid SCHEMBL19211700 | 0.73 | LMNA (0.64) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| Hydrochloric Acid SCHEMBL1017218 | 0.73 | LMNA (0.64) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| SCHEMBL7022399 | 0.71 | APOBEC3G (0.67) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| SCHEMBL3279839 | 0.71 | CA12 (0.63) | APOBEC3GKMT2ATDP1HSD11B1HTR6 | |
| SCHEMBL7764047 | 0.71 | APOBEC3G (0.54) | APOBEC3GKMT2ATDP1HSD11B1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143206-A | Pyrimidine-2,4-diamine derivatives for treatment of cancer | THOMAS HELLEDAYS STIFTELSE F R MEDICINSK FORSKNING | 2015-12-09 | — | — | CN | disclosed |