Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.36 |
| ▸ | ESR1 | P03372 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954334 | 0.91 | ESR2 (0.39) | ESR2ESR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28299085 | 0.87 | HDAC8 (0.36) | HDAC4HDAC2HDAC8ACMSDCYP2D6 | |
| SCHEMBL2254634 | 0.84 | CYP11B2 (0.39) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL17133924 | 0.82 | ESR2 (0.34) | HDAC4HDAC2HDAC8ACMSDESR2 | |
| SCHEMBL11166103 | 0.77 | HDAC4 (0.45) | HDAC4HDAC2HDAC8ACMSDESR2 | |
| SCHEMBL16950570 | 0.77 | POLB (0.35) | ESR2 | |
| SCHEMBL263798 | 0.75 | ACMSD (0.46) | HDAC4HDAC2HDAC8ACMSDESR2 | |
| SCHEMBL11300109 | 0.75 | HDAC4 (0.44) | HDAC4HDAC2HDAC8ACMSDESR2 | |
| SCHEMBL292337 | 0.73 | BACE1 (0.38) | ACMSDKMO | |
| SCHEMBL2029212 | 0.73 | ACMSD (0.44) | HDAC4HDAC2HDAC8ACMSDESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272931-A | Deuterium-substituted benzophenone derivatives and application thereof | TIANJIN INTERNAT JOINT ACADEMY OF BIOMEDICINE | 2016-01-27 | — | — | CN | disclosed |