SCHEMBL28044137

SCHEMBL28044137

CO[SiH](OC)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.49
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTR2B P41595 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HTR7 P34969 1/20 0.37
PGR P06401 1/20 0.35
MAPK1 P28482 1/20 0.35
MAOA P21397 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
DRD2 P14416 2/20 0.33
DRD3 P35462 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468716 0.80 PNMT (0.49) PNMTRAB9ANPC1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL17845923 0.77 PNMT (0.46) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL30103334 0.74 PNMT (0.63) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL524602 0.74 PNMT (0.63) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL8854649 0.73 DRD2 (0.54) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL2877998 0.72 PNMT (0.61) PNMTRAB9ANPC1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL4742132 0.71 PNMT (0.41) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL8971825 0.70 PNMT (0.46) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL22263591 0.70 PNMT (0.57) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL135721 0.70 PNMT (0.53) PNMTRAB9ANPC1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105189570-A Mixed internal donor structures for 1-olefin polymerization catalysts BASF SE 2015-12-23 CN disclosed