Decarboxylated Derivative

Decarboxylated Derivative

SCHEMBL28044138

NC(=O)CCCCC(N)=O.NCC1CCCCC1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.53
ALOX5 P09917 3/20 0.44
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.39
TARDBP Q13148 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
EPHX1 P07099 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HPGD P15428 1/20 0.37
KDM5A P29375 2/20 0.37
PHF8 Q9UPP1 2/20 0.37
KDM2A Q9Y2K7 2/20 0.37
KDM4C Q9H3R0 1/20 0.37
KDM4A O75164 1/20 0.37
SPHK1 Q9NYA1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17743478 0.89 PLG (0.54) CYP2D6ALOX5PLGPLATLMNA
SCHEMBL17743480 0.86 PLG (0.52) CYP2D6ALOX5PLGPLATLMNA
SCHEMBL9062020 0.85 ALOX5 (0.39) CYP2D6ALOX5PLGPLATLMNA
SCHEMBL931403 0.83 SIGMAR1 (0.54) ALOX5KMT2ATARDBPSIGMAR1EPHX1
SCHEMBL9203 0.83 SIGMAR1 (0.54) ALOX5KMT2ATARDBPSIGMAR1EPHX1
Decarboxylated Derivative SCHEMBL2813888 0.81 CYP2D6 (0.67) CYP2D6ALOX5PLGPLATLMNA
SCHEMBL13520 0.81 SIGMAR1 (0.57) ALOX5KMT2ATARDBPSIGMAR1EPHX1
SCHEMBL11010082 0.81 SIGMAR1 (0.57) ALOX5KMT2ATARDBPSIGMAR1EPHX1
SCHEMBL8860844 0.81 SIGMAR1 (0.57) ALOX5KMT2ATARDBPSIGMAR1EPHX1
SCHEMBL20408333 0.81 SIGMAR1 (0.57) ALOX5KMT2ATARDBPSIGMAR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377947-A Method for producing polyamide resin MITSUBISHI GAS CHEMICAL CO 2016-03-02 CN disclosed
CN-103635319-B Multilayer injection-molded body MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2015-12-02 CN disclosed