Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535990 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1KCNH2TDP1 | |
| SCHEMBL30641415 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1KCNH2TDP1 | |
| SCHEMBL4911892 | 0.81 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL6284370 | 0.80 | ALDH1A1 (0.37) | GABRA1GABRB2ALDH1A1ESR1TP53 | |
| SCHEMBL22781148 | 0.80 | GABRA1 (0.62) | GABRA1GABRB2ESR1KCNH2 | |
| SCHEMBL110775 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1TP53TDP1 | |
| SCHEMBL21565236 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2 | |
| SCHEMBL17329408 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2 | |
| SCHEMBL22745037 | 0.77 | PNMT (0.38) | ALDH1A1TP53TDP1ESR2MEN1 | |
| SCHEMBL16950434 | 0.77 | PDCD1 (0.48) | GABRA1GABRB2ALDH1A1ESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105273204-A | Block Copolymers, Their Manufacture And Their Use | KRATON POLYMERS US LLC | 2016-01-27 | — | — | CN | disclosed |