Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560042 | 0.83 | MAOA (0.64) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL4503147 | 0.79 | L3MBTL1 (0.53) | MAOAMAPTL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL2601918 | 0.78 | MAOA (1.00) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL3087928 | 0.77 | MAPK1 (0.67) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL7144984 | 0.77 | MAPT (0.67) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL20271919 | 0.77 | MAOA (0.69) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL11742788 | 0.77 | MAOA (0.73) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL5563589 | 0.77 | MAOA (0.55) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL12960466 | 0.77 | MAOA (0.69) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL29438168 | 0.76 | MAPT (0.71) | MAOAMAPTL3MBTL1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | claimed |
| CN-105481742-A | Anthraquinonyl thioureas with anti-leukemia activity and water solubility, and preparation method thereof | FUJIAN MEDICAL UNIV UNION HOSPITAL | 2016-04-13 | — | — | CN | claimed |
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | disclosed |
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | disclosed |
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | disclosed |
| CN-105481742-A | Anthraquinonyl thioureas with anti-leukemia activity and water solubility, and preparation method thereof | FUJIAN MEDICAL UNIV UNION HOSPITAL | 2016-04-13 | — | — | CN | disclosed |