Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334610 | 0.83 | ALDH1A1 (0.42) | TDP1CYP4F2CYP4A11MAOAMAOB | |
| SCHEMBL2920783 | 0.82 | CNR1 (0.39) | CYP4F2CYP4A11TAAR1DRD2DRD1 | |
| SCHEMBL27780984 | 0.80 | ALDH1A1 (0.50) | TDP1CYP4F2CYP4A11TAAR1MAOA | |
| SCHEMBL9651450 | 0.80 | TDP1 (0.46) | TDP1CYP4F2CYP4A11TAAR1MEN1 | |
| SCHEMBL2918719 | 0.78 | LPL (0.46) | TDP1 | |
| SCHEMBL7148962 | 0.78 | MEN1 (0.46) | MEN1KMT2AMAOAMAOB | |
| SCHEMBL4427688 | 0.78 | TDP1 (0.65) | TDP1TAAR1DRD2DRD1DRD4 | |
| SCHEMBL677236 | 0.77 | LPL (0.53) | TDP1 | |
| SCHEMBL1003365 | 0.77 | TP53 (0.44) | CYP1A2 | |
| SCHEMBL677064 | 0.76 | LPL (0.54) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143170-A | Substituted aromatic compounds for the treatment of pulmonary fibrosis, liver fibrosis, skin fibrosis and cardiac fibrosis | PROMETIC BIOSCIENCES INC | 2015-12-09 | — | — | CN | disclosed |