SCHEMBL7148962

SCHEMBL7148962

C[CH]c1cccc(CCCc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SIGMAR1 Q99720 3/20 0.45
HTR2A P28223 1/20 0.44
IGF1R P08069 1/20 0.43
ALOX15 P16050 1/20 0.43
MAOA P21397 3/20 0.42
MAOB P27338 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2918719 0.85 LPL (0.46) L3MBTL1
SCHEMBL677236 0.83 LPL (0.53) L3MBTL1
SCHEMBL677064 0.81 LPL (0.54) L3MBTL1
SCHEMBL677009 0.81 LPL (0.54) L3MBTL1
SCHEMBL2921023 0.81 LPL (0.54) L3MBTL1
SCHEMBL10387339 0.80 CALM1 (0.50) MAOAMAOB
SCHEMBL2920783 0.80 CNR1 (0.39) SIGMAR1
SCHEMBL25383248 0.78 MAOA (0.48) MAOAMAOB
SCHEMBL28044244 0.78 TDP1 (0.46) MEN1KMT2AMAOAMAOB
SCHEMBL9480031 0.76 MAOA (0.51) SIGMAR1IGF1RALOX15MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580478-B2 Latent acids and their use BASF SE (DE) 2013-11-12 US disclosed
EP-1320785-A2 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS Ciba SC Holding AG (CH) 2003-06-25 EP disclosed
WO-2002025376-A2 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-28 WO disclosed