Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201349 | 0.87 | MGLL (0.61) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| Thiourea SCHEMBL28139200 | 0.85 | MGLL (0.59) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL21603953 | 0.77 | MGLL (0.66) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1341392 | 0.75 | GAA (0.54) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| Anthraquinone SCHEMBL28138539 | 0.74 | MEN1 (0.67) | ALDH1A1KDM4ERECQLNPSR1NPC1 | |
| SCHEMBL319905 | 0.74 | MGLL (0.59) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5449571 | 0.73 | ALOX5 (0.49) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7080742 | 0.73 | MGLL (0.53) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4023191 | 0.72 | MGLL (0.57) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15158086 | 0.72 | MGLL (0.57) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | claimed |
| CN-105481742-A | Anthraquinonyl thioureas with anti-leukemia activity and water solubility, and preparation method thereof | FUJIAN MEDICAL UNIV UNION HOSPITAL | 2016-04-13 | — | — | CN | claimed |
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | disclosed |
| CN-105481742-B | One class has anti-leukocythemia liveness and water miscible anthraquinone thiourea and preparation method thereof | 福建医科大学附属协和医院 | 2017-03-29 | — | — | CN | disclosed |
| CN-105481742-A | Anthraquinonyl thioureas with anti-leukemia activity and water solubility, and preparation method thereof | FUJIAN MEDICAL UNIV UNION HOSPITAL | 2016-04-13 | — | — | CN | disclosed |