SCHEMBL3201349

SCHEMBL3201349

NC(=S)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.61
ALDH1A1 P00352 3/20 0.53
GRIN2D O15399 1/20 0.53
GRIN3B O60391 1/20 0.53
GRIN1 Q05586 1/20 0.53
GRIN2A Q12879 1/20 0.53
GRIN2B Q13224 1/20 0.53
GRIN2C Q14957 1/20 0.53
GRIN3A Q8TCU5 1/20 0.53
LMNA P02545 2/20 0.50
GAA P10253 1/20 0.50
KDM4E B2RXH2 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
AOC3 Q16853 1/20 0.46
RECQL P46063 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL28139200 0.98 MGLL (0.59) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL21603953 0.88 MGLL (0.66) MGLLALDH1A1GRIN2DGRIN3BGRIN1
Anthraquinone SCHEMBL28044251 0.87 MGLL (0.49) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL1341392 0.86 GAA (0.54) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL319905 0.84 MGLL (0.59) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL5449571 0.84 ALOX5 (0.49) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL4023191 0.83 MGLL (0.57) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL15158086 0.83 MGLL (0.57) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL9360060 0.83 MGLL (0.57) MGLLALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL6831548 0.83 MGLL (0.57) MGLLALDH1A1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-104693327-A Bi-metal semi-metallocene catalyst and preparation method and application thereof UNIV BEIJING CHEMICAL 2015-06-10 CN claimed
EP-1501528-B1 METHOD FOR EXTRACTING N,N'-DIBENZYLTHIOUREA FROM THE ROOT OF A PLANT OF THE PENTADIPLANDRACEAE FAMILY WANDJI THOMAS (FR) 2013-01-09 EP claimed
CN-1646149-B Method for extracting novel compound from root of plant of Oncomelania THOMAS WANDJI 2012-03-21 CN claimed
WO-2007090134-A2 USE OF VANILLOID RECEPTOR-1 ANTAGONISTS FOR THE PREVENTION AND TREATMENT OF GLAUCOMA ALCON MANUFACTURING, LTD. (US) 2007-08-09 WO claimed
EP-1029015-A4 CORROSION INHIBITOR FOR ALKANOLAMINE UNITS BETZDEARBORN INC (US) 2001-01-03 EP claimed
EP-1029015-A1 CORROSION INHIBITOR FOR ALKANOLAMINE UNITS BetzDearborn Inc (US) 2000-08-23 EP claimed
US-5885487-A ADDING TO AQUEOUS ALKANOLAMINE SOLUTION AND EFFECTIVE AMOUNT OF UREA, THIOUREA OR DERIVATIVES AS A CORROSION RESISTANT BETZDEARBORN INC. (US) 1999-03-23 US claimed
WO-1999010444-A1 CORROSION INHIBITOR FOR ALKANOLAMINE UNITS BETZDEARBORN INC. (US) 1999-03-04 WO claimed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN disclosed
CN-109963886-B Phosphoguanidine group IV metal olefin polymerization catalyst 陶氏环球技术有限责任公司 2023-01-06 CN disclosed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN disclosed
US-11066495-B2 Phosphaguanidine group IV metal olefin polymerization catalysts DOW GLOBAL TECHNOLOGY LLC (US) 2021-07-20 US disclosed
EP-3519470-B1 PHOSPHAGUANIDINE GROUP IV METAL OLEFIN POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-21 EP disclosed
WO-1999062897-A1 HIV INTEGRASE INHIBITORS MERCK & CO., INC. (US) 1999-12-09 WO disclosed
US-5885487-A ADDING TO AQUEOUS ALKANOLAMINE SOLUTION AND EFFECTIVE AMOUNT OF UREA, THIOUREA OR DERIVATIVES AS A CORROSION RESISTANT BETZDEARBORN INC. (US) 1999-03-23 US disclosed
WO-1999010444-A1 CORROSION INHIBITOR FOR ALKANOLAMINE UNITS BETZDEARBORN INC. (US) 1999-03-04 WO disclosed
EP-0384665-A2 Optical recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-08-29 EP disclosed
US-4316779-A THIOUREA COMPOUND BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1982-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066495-B2 Phosphaguanidine group IV metal olefin polymerization catalysts POLG, ODC1, RNGTT MGLL 1257/4885ALDH1A1 1383/4885GRIN2D 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.