Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.66 |
| ▸ | AR | P10275 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.59 |
| ▸ | GABRP | O00591 | 3/20 | 0.59 |
| ▸ | GABRD | O14764 | 3/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645880 | 0.87 | AR (0.50) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL312583 | 0.85 | AR (0.61) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL28637042 | 0.81 | CYP3A4 (0.57) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| 5-Hydroxyflavone SCHEMBL158303 | 0.80 | AR (1.00) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| 5-Hydroxyflavone SCHEMBL30630415 | 0.80 | AR (1.00) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| 5-Hydroxyflavone SCHEMBL2390993 | 0.80 | AR (1.00) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL4183286 | 0.79 | AHR (0.61) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| 5-Hydroxyflavone SCHEMBL28317755 | 0.78 | AR (0.97) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| 5-Hydroxyflavone SCHEMBL2390943 | 0.78 | AR (0.97) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL11651069 | 0.77 | ALDH1A1 (0.67) | CYP3A4ARMAPTSMN1; SMN2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111263-B | Flavone compound isolated and purified from shepherd's purse and its production and use | 南阳师范学院 | 2017-07-28 | — | — | CN | disclosed |
| CN-105111263-A | Flavones separated and purified from shepherd's purse, and preparation method and application thereof | UNIV NANYANG NORMAL | 2015-12-02 | — | — | CN | disclosed |