Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3802190 | 0.96 | CA1 (0.33) | CA1CA4FAHD1 | |
| Bicarbonate SCHEMBL11228006 | 0.91 | — | — | |
| Bicarbonate SCHEMBL3326642 | 0.91 | CA4 (0.46) | CA1CA4FAHD1CA2 | |
| Sulfuric Acid SCHEMBL11215157 | 0.86 | MEN1 (0.33) | — | |
| Bicarbonate SCHEMBL5586484 | 0.80 | — | — | |
| Sulfurous Acid SCHEMBL27336542 | 0.80 | — | — | |
| Bicarbonate SCHEMBL532723 | 0.80 | CA4 (0.50) | CA1CA4FAHD1CA2 | |
| Bicarbonate SCHEMBL1331961 | 0.80 | — | — | |
| Bicarbonate SCHEMBL711064 | 0.80 | CA4 (0.50) | CA1CA4FAHD1CA2 | |
| Bicarbonate SCHEMBL3261 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880058-B | A kind of precipitated chalk production technique of falling magnesium increasing calcium | HEBEI UNIVERSITY OF TECHNOLOGY (CN) | 2016-01-20 | — | — | CN | disclosed |