Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 3/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412314 | 0.80 | KIF20B (0.42) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL411963 | 0.76 | KMO (0.47) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL411960 | 0.74 | SLC6A3 (0.41) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL31267238 | 0.74 | MEN1 (0.40) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL21634939 | 0.74 | MEN1 (0.40) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL28912077 | 0.72 | GRM2 (0.44) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL21634717 | 0.70 | TTR (0.47) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL31267253 | 0.70 | TTR (0.47) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL21634704 | 0.68 | NOTUM (0.46) | KMT2ANPSR1MEN1MAPTHTT | |
| SCHEMBL27924528 | 0.68 | CNR1 (0.34) | KMT2AMEN1MAPTCNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103118680-B | Heteroaryl carboxamides | HOFFMAN-LA ROCHE LTD. (CH) | 2015-12-16 | — | — | CN | disclosed |