Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840900 | 0.92 | XDH (0.54) | MAPTGABRA5L3MBTL1XDHACHE | |
| SCHEMBL795937 | 0.84 | MAPT (0.61) | MAPTGABRA5L3MBTL1XDHACHE | |
| SCHEMBL567481 | 0.81 | PARP15 (0.51) | XDH | |
| SCHEMBL4681119 | 0.81 | MAPT (0.56) | MAPTL3MBTL1XDHACHEHCAR3 | |
| SCHEMBL840394 | 0.81 | MAPT (0.50) | MAPTGABRA5L3MBTL1HCAR3 | |
| SCHEMBL840841 | 0.80 | MAPT (0.55) | MAPTGABRA5L3MBTL1HCAR3 | |
| SCHEMBL797553 | 0.78 | MAPT (0.47) | MAPTL3MBTL1HCAR3 | |
| SCHEMBL1928108 | 0.78 | MCHR1 (0.42) | GABRA5XDH | |
| SCHEMBL840756 | 0.76 | HCAR3 (0.60) | MAPTL3MBTL1HCAR3 | |
| SCHEMBL839875 | 0.75 | HCAR3 (0.56) | MAPTGABRA5L3MBTL1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103118680-B | Heteroaryl carboxamides | HOFFMAN-LA ROCHE LTD. (CH) | 2015-12-16 | — | — | CN | disclosed |