Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044545 | 0.84 | MAPT (0.35) | MAPTALDH1A1 | |
| SCHEMBL590610 | 0.84 | MAPT (0.33) | MAPTCYP3A4MAPK1ALDH3A1TP53 | |
| SCHEMBL28044442 | 0.72 | NR3C1 (0.32) | — | |
| SCHEMBL3211653 | 0.72 | MAPT (0.47) | MAPTCYP3A4MAPK1MEN1ALDH1A1 | |
| SCHEMBL28044438 | 0.71 | HCAR3 (0.45) | MAPTCYP3A4MAPK1ALDH3A1TP53 | |
| SCHEMBL589760 | 0.71 | MAPT (0.38) | MAPTHTTHCAR3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28824557 | 0.70 | HCAR3 (0.44) | MAPTCYP3A4MAPK1ALDH3A1TP53 | |
| SCHEMBL589567 | 0.69 | MAPT (0.42) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL590762 | 0.67 | MAPT (0.35) | MAPTALDH1A1 | |
| SCHEMBL457530 | 0.66 | KAT2B (0.36) | MAPTMAPK1HTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |