Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589760 | 0.84 | MAPT (0.38) | MAPTHTR7KDM4EALDH1A1 | |
| SCHEMBL28044527 | 0.84 | MAPT (0.32) | MAPTALDH1A1 | |
| SCHEMBL589567 | 0.82 | MAPT (0.42) | MAPTHTR7KDM4EALDH1A1 | |
| SCHEMBL590762 | 0.80 | MAPT (0.35) | MAPTHTR7KDM4EALDH1A1 | |
| SCHEMBL3211653 | 0.77 | MAPT (0.47) | MAPTALDH1A1 | |
| SCHEMBL592328 | 0.76 | HTR7 (0.49) | HTR7ALDH1A1 | |
| SCHEMBL591011 | 0.75 | HTR7 (0.50) | MAPTHTR7KDM4EALDH1A1 | |
| SCHEMBL590610 | 0.72 | MAPT (0.33) | MAPTALDH1A1 | |
| SCHEMBL28044536 | 0.70 | HTR7 (0.33) | HTR7 | |
| SCHEMBL28044441 | 0.69 | HCAR3 (0.41) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |