Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044449 | 0.73 | CACNA1F (0.42) | ALDH1A1KDM4ELMNAHRH3 | |
| SCHEMBL8721629 | 0.72 | ALDH1A1 (0.44) | ALDH1A1LMNATSHR | |
| SCHEMBL2292289 | 0.71 | MAP2K4 (0.38) | ALDH1A1SMN1; SMN2NR3C1CA2NR3C2 | |
| SCHEMBL195978 | 0.71 | KIF11 (0.42) | ALDH1A1KDM4EHPGDHTTSMN1; SMN2 | |
| SCHEMBL9244412 | 0.70 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGDCA2HRH3 | |
| SCHEMBL28044536 | 0.69 | HTR7 (0.33) | NR3C2 | |
| SCHEMBL28044453 | 0.69 | HTR7 (0.33) | NR3C2 | |
| SCHEMBL29077531 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDCA2HRH3 | |
| SCHEMBL2035839 | 0.68 | KIF11 (0.47) | SLC6A4SLC6A2SLC6A3NR3C1CA2 | |
| SCHEMBL1570303 | 0.68 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |