Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481127 | 0.83 | DRD2 (0.47) | DRD2RXRARXRBRXRGRBP4 | |
| SCHEMBL8136300 | 0.83 | ALDH1A1 (0.58) | ARRXRARXRBRXRGHTT | |
| SCHEMBL2317520 | 0.83 | RXRA (0.46) | ARDRD2RXRARXRBRXRG | |
| SCHEMBL20228046 | 0.82 | KDM4E (0.53) | DRD2HTTALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL7039560 | 0.81 | MRGPRX4 (0.48) | DRD2RXRARXRBRXRGRBP4 | |
| SCHEMBL18833336 | 0.81 | RXRA (0.47) | ARDRD2RXRARXRBRXRG | |
| SCHEMBL30628194 | 0.80 | HTT (0.48) | ARRXRARXRBRXRGHTT | |
| SCHEMBL17420735 | 0.80 | HTT (0.48) | ARRXRARXRBRXRGHTT | |
| SCHEMBL10300150 | 0.80 | ALDH1A1 (0.44) | ARRXRARXRBRXRGHTT | |
| SCHEMBL2974587 | 0.80 | MAPT (0.56) | HTTALDH1A1L3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073715-A | Dihydropyridazine-3,5-dione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |