SCHEMBL28044957

SCHEMBL28044957

COC(=O)C[C@H](CCO)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
KCNA5 P22460 3/20 0.47
F2 P00734 6/20 0.46
F10 P00742 5/20 0.46
PRSS1 P07477 4/20 0.45
KMT2A Q03164 1/20 0.44
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
GABBR2 O75899 1/20 0.42
GABBR1 Q9UBS5 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1811944 1.00 ALDH1A1 (0.55) ALDH1A1KCNA5F2F10PRSS1
SCHEMBL7995142 0.88 ALDH1A1 (0.67) ALDH1A1KCNA5KMT2AFNTAFNTB
SCHEMBL27323723 0.87 ALDH1A1 (0.55) ALDH1A1KCNA5F2F10PRSS1
SCHEMBL13136720 0.85 ALDH1A1 (0.54) ALDH1A1KCNA5F2F10PRSS1
SCHEMBL8265702 0.85 ALDH1A1 (0.54) ALDH1A1KCNA5F2F10PRSS1
SCHEMBL9424092 0.84 ALDH1A1 (0.52) ALDH1A1KCNA5F2F10PRSS1
SCHEMBL6579159 0.84 HTT (0.54) ALDH1A1F2F10PRSS1KMT2A
SCHEMBL14691320 0.83 F2 (0.50) ALDH1A1F2F10PRSS1KMT2A
SCHEMBL12268202 0.83 ALDH1A1 (0.61) ALDH1A1KCNA5KMT2AFNTAFNTB
SCHEMBL22303151 0.83 ALDH1A1 (0.57) ALDH1A1KCNA5KMT2AGABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105177069-A Method for cell production of (S)-hydroxyethyl methyl phenylpropionate UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-12-23 CN disclosed