SCHEMBL891365

SCHEMBL891365

CC(N=C=O)OC(=O)C=CC(=O)OC(C)N=C=O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.43
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
CA12 O43570 1/20 0.31
AKR1B10 O60218 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
AKR1B1 P15121 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891364 1.00 HCAR2 (0.43) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL27511152 0.92 HCAR2 (0.57) HCAR2
SCHEMBL9809844 0.92 HCAR2 (0.57) HCAR2
SCHEMBL3697116 0.90 HCAR2 (0.35) HCAR2
SCHEMBL3697113 0.90 HCAR2 (0.35) HCAR2
SCHEMBL10854431 0.88 HCAR2 (0.47) HCAR2CA12CA1CA2CA7
SCHEMBL10854417 0.88 HCAR2 (0.47) HCAR2CA12CA1CA2CA7
Ethylene Glycol SCHEMBL3701779 0.84 HCAR2 (0.32) HCAR2
SCHEMBL195840 0.83 TSHR (0.39)
SCHEMBL21409479 0.82 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747295-A1 OPTICAL MATERIAL DERIVED FROM A PREPOLYMER OBTAINED FROM A HETERODIFUNCTIONAL ALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2026-05-27 EP claimed
EP-4747293-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A TERMINAL DIALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2026-05-27 EP claimed
EP-4747294-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A HETERODIFUNCTIONAL ALKYNE COMPOUND Essilor International (FR) 2026-05-27 EP claimed
US-20260117015-A1 METHOD OF CURING A POLYTHIOURETHANE BASED SUBSTRATE WITH A SALT CATALYST ESSILOR INT (FR) 2026-04-30 US claimed
EP-4634258-A1 METHOD OF CURING A POLYTHIOURETHANE BASED SUBSTRATE TOLERANT TO WATER Essilor International (FR) 2025-10-22 EP claimed
EP-4598973-A1 METHOD OF CURING A POLYTHIOURETHANE BASED SUBSTRATE WITH A SALT CATALYST Essilor International (FR) 2025-08-13 EP claimed
WO-2025017197-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A HETERODIFUNCTIONAL ALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2025-01-23 WO claimed
WO-2025017201-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A TERMINAL DIALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2025-01-23 WO claimed
WO-2025017198-A1 OPTICAL MATERIAL DERIVED FROM A PREPOLYMER OBTAINED FROM A HETERODIFUNCTIONAL ALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2025-01-23 WO claimed
WO-2024208839-A1 METHOD OF CURING A POLYTHIOURETHANE-BASED SUBSTRATE FROM A PRE-POLYMER ESSILOR INTERNATIONAL (FR) 2024-10-10 WO claimed
EP-4442724-A1 METHOD OF CURING A POLYTHIOURETHANE-BASED SUBSTRATE FROM A PRE-POLYMER Essilor International (FR) 2024-10-09 EP claimed
WO-2024126747-A1 METHOD OF CURING A POLYTHIOURETHANE BASED SUBSTRATE TOLERANT TO WATER ESSILOR INTERNATIONAL (FR) 2024-06-20 WO claimed
WO-2024074596-A1 METHOD OF CURING A POLYTHIOURETHANE BASED SUBSTRATE WITH A SALT CATALYST ESSILOR INTERNATIONAL (FR) 2024-04-11 WO claimed
EP-4747294-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A HETERODIFUNCTIONAL ALKYNE COMPOUND Essilor International (FR) 2026-05-27 EP disclosed
EP-4747293-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A TERMINAL DIALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2026-05-27 EP disclosed
EP-4747295-A1 OPTICAL MATERIAL DERIVED FROM A PREPOLYMER OBTAINED FROM A HETERODIFUNCTIONAL ALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2026-05-27 EP disclosed
US-4446292-A Moisture curable compositions containing reaction products of hydrophobic polyols and monomer organosilicon-containing substances PPG INDUSTRIES, INC. (US) 1984-05-01 US disclosed
US-4125570-A Method of stabilizing the gloss retention of thermosetting resins containing hydroxyl groups PPG INDUSTRIES, INC. (US) 1978-11-14 US disclosed
US-3962522-A Poly(esterurethane) coating cured with an aminoplast on a solid substrate PPG INDUSTRIES, INC. (US) 1976-06-08 US disclosed
US-3954899-A URETHANES AND AMINE-ALDEHYDE RESINS PPG INDUSTRIES, INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117015-A1 METHOD OF CURING A POLYTHIOURETHANE BASED SUBSTRATE WITH A SALT CATALYST NCAPH, CTH, CRYAA HCAR2 3472/4885KEAP1 476/4885NFE2L2 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.