SCHEMBL28045112

SCHEMBL28045112

COc1ccc(-c2cccc3ncsc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
ACACA Q13085 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
KDM4E B2RXH2 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PKM P14618 1/20 0.41
PTGS2 P35354 2/20 0.41
APP P05067 1/20 0.41
SYK P43405 1/20 0.40
AURKB Q96GD4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516596 0.80 ALDH1A1 (0.45) KDM4EALDH1A1L3MBTL1
SCHEMBL1638443 0.79 CDK5 (0.42) ABL1CLK4ALDH1A1LMNANPC1
SCHEMBL24156072 0.79 NPC1 (0.38) KDM4EALDH1A1LMNAL3MBTL1NPC1
SCHEMBL29283132 0.78 APP (0.44) ALDH1A1KMT2AAPPMAPT
SCHEMBL27177778 0.76 LOXL2 (0.44) KDM4EALDH1A1NPC1SMN1; SMN2
SCHEMBL5544603 0.74 ACACA (0.44) ABL1ABCB1BCRACACACLK4
SCHEMBL17691846 0.72 ERN1 (0.40) ALDH1A1ADORA2A
SCHEMBL17231497 0.72 ALDH1A1 (0.38) CLK4ALDH1A1
SCHEMBL17231472 0.72 ALDH1A1 (0.38) CLK4ALDH1A1
SCHEMBL5153695 0.71 ABL1 (0.46) ABL1ABCB1BCRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103756670-B Electroluminescent organic material and its preparation method and application SHANGHAI HEHUI PHOTOELECTRICITY CO., LTD. (CN) 2015-12-09 CN disclosed