Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27518136 | 0.82 | ALOX15 (0.57) | CA4ALDH1A1ALOX15ACHEHSD17B10 | |
| SCHEMBL29356215 | 0.81 | — | — | |
| SCHEMBL33821 | 0.81 | — | — | |
| SCHEMBL4866842 | 0.81 | ALOX15 (0.65) | ALDH1A1ALOX15ACHEHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL8581193 | 0.79 | ALOX15 (0.62) | ALDH1A1ALOX15ACHEHSD17B10MAPT | |
| SCHEMBL780305 | 0.75 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10MAPTTHRB | |
| Hydrochloric Acid SCHEMBL558064 | 0.74 | ALDH1A1 (0.70) | ALDH1A1ALOX15HSD17B10MAPTTHRB | |
| SCHEMBL29878426 | 0.73 | CYP3A4 (0.65) | ALDH1A1ALOX15HSD17B10MAPTTHRB | |
| Anisole SCHEMBL28311263 | 0.72 | CA4 (0.74) | CA4ALDH1A1ACHETDP1CYP3A4 | |
| Anisole SCHEMBL27664648 | 0.72 | CYP2A6 (0.71) | CA4ACHEMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787952-B | A kind of method of synthesis of natural product C lausenine | Changzhou University (CN) | 2016-01-27 | — | — | CN | claimed |