SCHEMBL780305

SCHEMBL780305

COc1ccc(N)c(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
MEN1 O00255 2/20 0.67
MAPT P10636 2/20 0.67
THRB P10828 2/20 0.67
KMT2A Q03164 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
KDM4E B2RXH2 1/20 0.67
GAA P10253 1/20 0.67
RECQL P46063 1/20 0.67
BLM P54132 1/20 0.67
MCL1 Q07820 1/20 0.67
CYP3A4 P08684 4/20 0.57
NPC1 O15118 4/20 0.55
RAB9A P51151 2/20 0.53
MAPK1 P28482 3/20 0.52
TRIM24 O15164 1/20 0.52
TYR P14679 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL558064 0.98 ALDH1A1 (0.70) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL29878426 0.84 CYP3A4 (0.65) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL245052 0.82 ALDH1A1 (0.96) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL30040301 0.81 NR4A1 (0.61) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL436522 0.81 NR4A1 (0.61) ALDH1A1MEN1MAPTTHRBKMT2A
Hydrochloric Acid SCHEMBL3020904 0.80 ALDH1A1 (1.00) ALDH1A1MEN1MAPTTHRBKMT2A
Mequinol SCHEMBL6750117 0.79 ALDH1A1 (0.81) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL27657589 0.79 MEN1 (0.45) ALDH1A1MEN1MAPTTHRBKMT2A
Hydrochloric Acid SCHEMBL10770715 0.79 NR4A1 (0.58) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL19809245 0.79 NR4A1 (0.58) ALDH1A1MEN1MAPTTHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103491937-B Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof 宝洁公司 2016-08-31 CN claimed
CN-103491937-A Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof PROCTER & GAMBLE 2014-01-01 CN claimed
US-20030069149-A1 Inhibitor for inhibiting carbonaceous powder from heating up/spontaneously igniting and method of inhibiting carbonaceous powder from heating up/spontaneously igniting LION CORPORATION (JP) 2003-04-10 US claimed
EP-0070016-A1 Method and composition for increasing reproduction in mammalian and avian species THE UNIVERSITY OF UTAH (US) 1983-01-19 EP claimed
EP-4741389-A1 KAT6 INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2026-05-13 EP disclosed
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME CHECKMATE THERAPEUTICS INC. (KR) 2026-01-22 US disclosed
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
WO-2025245046-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2025-11-27 WO disclosed
CN-119948034-A Novel peptide-based nitrile compound and application thereof 上海壹迪生物技术有限公司 2025-05-06 CN disclosed
CN-113226470-B Rifamycin analogs and antibody-drug conjugates thereof 瑞泽恩制药公司 2025-05-06 CN disclosed
EP-4543863-A1 FERROPTOSIS INHIBITORS AND USES THEREOF University Of Ottawa (CA) 2025-04-30 EP disclosed
WO-2025036382-A1 SULFONAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海复宏汉霖生物医药有限公司 2025-02-20 WO disclosed
EP-0030436-B1 2-HYDROXYOXANILIC ACID DERIVATIVES AND SALTS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-05-09 EP disclosed
US-4429133-A OPTICAL BRIGHTENERS FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1984-01-31 US disclosed
EP-0070016-A1 Method and composition for increasing reproduction in mammalian and avian species THE UNIVERSITY OF UTAH (US) 1983-01-19 EP disclosed
EP-0030436-A1 2-Hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1981-06-17 EP disclosed
US-4157444-A ANTIPSYCHOTIC, NEUROLEPTIC AMERICAN CYANAMID COMPANY (US) 1979-06-05 US disclosed
US-4144235-A ANTIPSYCHOTIC, NEUROLEPTIC AMERICAN CYANAMID COMPANY (US) 1979-03-13 US disclosed
US-4003875-A ULTRAVIOLET ABSORBERS CIBA-GEIGY CORPORATION (US) 1977-01-18 US disclosed
US-3996210-A OPTICAL BRIGHTENERS SANDOZ LTD. (CH) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069149-A1 Inhibitor for inhibiting carbonaceous powder from heating up/spontaneously igniting and method of inhibiting carbonaceous powder from heating up/spontaneously igniting CBS, UPP1, NOS1 ALDH1A1 4031/4885MEN1 982/4885MAPT 436/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR ALDH1A1 3728/4885MEN1 1417/4885MAPT 4571/4885
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME NAMPT, NAPRT, NNT ALDH1A1 789/4885MEN1 2486/4885MAPT 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.