4-Hydroxyacetophenone

4-Hydroxyacetophenone

SCHEMBL28045206

CC(=O)OC(C)=O.CC(=O)c1ccc(O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.68
HPGD P15428 3/20 0.52
MAPT P10636 3/20 0.52
RAB9A P51151 1/20 0.52
CA12 O43570 4/20 0.50
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA7 P43166 4/20 0.50
CA9 Q16790 4/20 0.50
CA14 Q9ULX7 4/20 0.50
ESR1 P03372 3/20 0.48
ESR2 Q92731 3/20 0.48
LMNA P02545 2/20 0.48
PKM P14618 1/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
KMT2A Q03164 1/20 0.46
CA5A P35218 2/20 0.46
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Hydroxyacetophenone SCHEMBL8934912 0.88 HSD17B1 (0.85) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL40866 0.88 HSD17B1 (0.85) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL28050008 0.85 HSD17B1 (0.81) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL28895846 0.85 HSD17B1 (0.81) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL8744798 0.85 HSD17B1 (0.81) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL31385561 0.85 HSD17B1 (0.81) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL27639603 0.85 HSD17B1 (0.81) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL9480590 0.85 HSD17B1 (0.81) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL15193889 0.84 HSD17B1 (0.71) HSD17B1HPGDMAPTRAB9ACA12
4-Hydroxyacetophenone SCHEMBL27592796 0.83 HSD17B1 (0.77) HSD17B1HPGDMAPTRAB9ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103360249-B To acetoxyl methyl phenyl carbinol and the preparation method to acetoxystyrene SINOPEC CORP. (CN) 2015-12-02 CN disclosed