Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxyacetophenone SCHEMBL8934912 | 0.97 | HSD17B1 (0.85) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL40866 | 0.97 | HSD17B1 (0.85) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL31385561 | 0.94 | HSD17B1 (0.81) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL28895846 | 0.94 | HSD17B1 (0.81) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL9480590 | 0.94 | HSD17B1 (0.81) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL27639603 | 0.94 | HSD17B1 (0.81) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL28050008 | 0.94 | HSD17B1 (0.81) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL27592796 | 0.92 | HSD17B1 (0.77) | HSD17B1HPGDMAPTLMNAESR1 | |
| 4-Hydroxyacetophenone SCHEMBL27598207 | 0.92 | HSD17B1 (0.77) | HSD17B1HPGDMAPTLMNAESR1 | |
| SCHEMBL4085842 | 0.90 | HSD17B1 (1.00) | HSD17B1HPGDMAPTLMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469742-B1 | Production of acetaminophen | HOECHST CELANESE CORP (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5235090-A | Synthesis of 2-(4'-aminophenyloxy) alkanoic acids & acids & esters & their derivatives | HOECHST CELANESE CORP. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5155273-A | Adding Beckmann rearrangement catalyst having electrophilic carbon atom to 4-hydroxyacetophenone oxime | HOECHST CELANESE CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0469742-A2 | Production of acetaminophen | HOECHST CELANESE CORPORATION (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5008439-A | Synthesis of 2-(4-hydroxyphenoxy) alkanoic acid esters | HOECHST CELANESE CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-4935522-A | Process for producing ethyl 2-[4'-(6\"-chloro-2\"-benzoxazolyloxy)phenoxy]propionate | HOECHST CELANESE CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4908476-A | Synthesis of 2-(4-hydroxyphenoxy)alkanoic acids | HOECHST CELANESE CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |
| US-4883901-A | Synthesis of 2-(4-aminophenoxy)alkanoic acids and esters and their derivatives | HOECHST CELANESE CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0334595-A2 | Synthesis of 2-(4-hydroxyphenoxy)alkanoic acids | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0334596-A2 | Synthesis of 2-(4-hydroxyphenoxy)alkanoic acid esters | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0334597-A1 | A process for producing ethyl 2-(4'-(6\"-chloro-2\"-benzox-azolyl) phenoxy) proprionate | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0334598-A2 | Synthesis of 2-(4'aminophenoxy) alkanoic acids and esters and their derivatives | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |