4-Hydroxyacetophenone

4-Hydroxyacetophenone

SCHEMBL40866

CC(=O)c1ccc(O)cc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.85
HPGD P15428 3/20 0.60
MAPT P10636 3/20 0.60
LMNA P02545 2/20 0.60
ESR1 P03372 2/20 0.60
ESR2 Q92731 2/20 0.60
PKM P14618 1/20 0.60
HTT P42858 1/20 0.60
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
CA5A P35218 2/20 0.57
CA12 O43570 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Hydroxyacetophenone SCHEMBL8934912 1.00 HSD17B1 (0.85) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL28895846 0.97 HSD17B1 (0.81) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL28050008 0.97 HSD17B1 (0.81) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL9480590 0.97 HSD17B1 (0.81) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL8744798 0.97 HSD17B1 (0.81) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL27639603 0.97 HSD17B1 (0.81) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL31385561 0.97 HSD17B1 (0.81) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL27598207 0.95 HSD17B1 (0.77) HSD17B1HPGDMAPTLMNAESR1
4-Hydroxyacetophenone SCHEMBL27592796 0.95 HSD17B1 (0.77) HSD17B1HPGDMAPTLMNAESR1
SCHEMBL7940485 0.92 LMNA (0.75) HSD17B1HPGDMAPTLMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 28519 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748367-A2 SUNSCREEN COMPOSITION DSM IP Assets B.V. (NL) 2026-05-27 EP claimed
CN-122094650-A Composition for caring keratin materials and body film comprising the same 2026-05-26 CN claimed
CN-122075351-A Acne-removing composition, and preparation method and application thereof 2026-05-26 CN claimed
CN-122075321-A Shampoo essence based on lactic acid and preparation method thereof 2026-05-26 CN claimed
CN-122075362-A Preparation method of eriodictyol-containing lemon fruit extract and application of eriodictyol-containing lemon fruit extract in relaxation 2026-05-26 CN claimed
CN-122075332-A Composition, preparation method thereof and sun-screening composition 2026-05-26 CN claimed
CN-121533943-B Relief and repair composition and application thereof in cosmetics GUANGZHOU DANKE NETWORK TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-121550087-B Rapid film forming repairing composition and preparation method and application thereof SHANGHAI SHAWYA BIOTECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-120204075-B Antiseptic and antibacterial composition and preparation method and application thereof Guyu Biotechnology Group Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12636246-B2 Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound L'OREAL (FR) 2026-05-26 US claimed
EP-0001431-A1 Enamel binder suitable for cathodic electrodeposition BASF Aktiengesellschaft (DE) 1979-04-18 EP claimed
US-4148968-A COLORLESS TONER, A POLYMER OR CLAY AND A FATTY ACID OR DERIVATIVE CANON KABUSHIKI KAISHA (JP) 1979-04-10 US claimed
US-4135033-A HEAT DISSOCIABLE MOLECULAR COMPLEX BARRIER LAYER LAWTON WILLIAM R 1979-01-16 US claimed
EP-0000107-A1 Metallic or metallised article coated with a polyphenylene oxide film carrying reactive groups, its electrochemical preparation and its use ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1978-12-20 EP claimed
US-4075340-A ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS PARCOR (FR) 1978-02-21 US claimed
US-4025399-A ELECTRICAL, RECORDING LAYER WITH A CONDUCTIVE AGENT, A LEUCO BASE AND A PHENOLIC RESIN CANON KABUSHIKI KAISHA (JA) 1977-05-24 US claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
US-3984605-A Heat sensitive recording material containing decolorizing agent MITSUBISHI PAPER MILLS, LTD. (JA) 1976-10-05 US claimed
US-3959319-A FREE FLOWING CRYSTALS THE UPJOHN COMPANY (US) 1976-05-25 US claimed