Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408746 | 0.80 | SMN1; SMN2 (0.45) | HSD17B10SMN1; SMN2POLBCXCR4ANPEP | |
| SCHEMBL9329894 | 0.78 | SMN1; SMN2 (0.43) | HSD17B10SMN1; SMN2POLBCXCR4ANPEP | |
| SCHEMBL9801548 | 0.78 | SMN1; SMN2 (0.46) | HSD17B10SMN1; SMN2POLBCXCR4ANPEP | |
| SCHEMBL22320733 | 0.78 | SMN1; SMN2 (0.46) | HSD17B10SMN1; SMN2POLBCXCR4ANPEP | |
| SCHEMBL8370583 | 0.77 | ANPEP (0.44) | HSD17B10SMN1; SMN2POLBCXCR4ANPEP | |
| SCHEMBL1408997 | 0.77 | SIGMAR1 (0.39) | SMN1; SMN2SIGMAR1CHRM5CHRM3MEN1 | |
| Hydrochloric Acid SCHEMBL6960637 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6956666 | 0.75 | SIGMAR1 (0.38) | SMN1; SMN2SIGMAR1CHRM5CHRM3MEN1 | |
| Methane SCHEMBL2871267 | 0.75 | SIGMAR1 (0.38) | SMN1; SMN2SIGMAR1CHRM5CHRM3MEN1 | |
| SCHEMBL1904293 | 0.75 | SMN1; SMN2 (0.41) | HSD17B10SMN1; SMN2POLBCXCR4ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111142-A | Preparation method of hydroxypiperaquine and phosphate thereof | SUZHOU MOER PHARMACEUTICAL CO LTD | 2015-12-02 | — | — | CN | claimed |
| CN-105111142-B | Hydroxypiperaquin and its method for production of phosphate salt | 苏州摩尔医药有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-105111142-A | Preparation method of hydroxypiperaquine and phosphate thereof | SUZHOU MOER PHARMACEUTICAL CO LTD | 2015-12-02 | — | — | CN | disclosed |
| CN-105111142-A | Preparation method of hydroxypiperaquine and phosphate thereof | SUZHOU MOER PHARMACEUTICAL CO LTD | 2015-12-02 | — | — | CN | disclosed |