Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74380 | 0.80 | HTR6 (0.60) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL29490409 | 0.80 | HTR6 (0.60) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL29969255 | 0.79 | TRPV4 (0.49) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL1713241 | 0.79 | TRPV4 (0.49) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL22980481 | 0.79 | TRPV4 (0.53) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL5984084 | 0.79 | TRPV4 (0.49) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL29651874 | 0.78 | TRPV4 (0.47) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL3966892 | 0.78 | EDNRA (0.49) | TRPV4HTR6CA2CA1CA12 | |
| SCHEMBL18096559 | 0.78 | TRPV4 (0.47) | TRPV4HTR6NFE2L2KCNH2CA2 | |
| SCHEMBL17472499 | 0.77 | HTR6 (0.72) | HTR6KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608350-B | Triazolopyridine compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |