Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490409 | 1.00 | HTR6 (0.60) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| SCHEMBL7205989 | 0.82 | TRPV4 (0.42) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| SCHEMBL31352974 | 0.82 | HTR6 (0.77) | HTR6NFE2L2KCNH2CA12CA1 | |
| SCHEMBL31387938 | 0.82 | TRPV4 (0.42) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| SCHEMBL22980481 | 0.82 | TRPV4 (0.53) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| SCHEMBL1713241 | 0.82 | TRPV4 (0.49) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| SCHEMBL5984084 | 0.82 | TRPV4 (0.49) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| SCHEMBL29969255 | 0.82 | TRPV4 (0.49) | HTR6TRPV4NFE2L2KCNH2CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL66189 | 0.81 | CA1 (0.68) | HTR6TRPV4NFE2L2CA12CA1 | |
| SCHEMBL29651874 | 0.80 | TRPV4 (0.47) | HTR6TRPV4NFE2L2KCNH2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119425423-A | Positively charged composite membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-114524811-B | LXH0307 and LXH0308 as small molecule inhibitors for gene editing and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-01-24 | — | — | CN | claimed |
| CN-118496175-A | TRADD inhibitor derivative and preparation method and application thereof | 安徽医科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-114524811-A | LXH0307 and LXH0308 as small molecule inhibitors of gene editing and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-05-24 | — | — | CN | claimed |
| CN-111100044-B | Preparation method of alkyl zinc sulfinate series compounds | 鹤壁元昊化工有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-110467551-A | A kind of 4- methoxyl group-N- (1- naphthalene) benzene sulfonamide STAT3 micromolecular inhibitor and its preparation and application | UNIV WENZHOU MEDICAL | 2019-11-19 | — | — | CN | claimed |
| CN-110156942-A | A kind of preparation method and application of comb block polycarboxylic acid super-plasticizer | 中科广化（重庆）新材料研究院有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-109694338-A | A kind of methoxyacetophenone derivative and preparation method thereof, application | 河南科技大学 | 2019-04-30 | — | — | CN | claimed |
| CN-109678784-A | Thioetherification Benzazole compounds and preparation method thereof | 天津师范大学 | 2019-04-26 | — | — | CN | claimed |
| CN-107176915-B | A kind of synthetic method of alkene sulfone compound | 同济大学 | 2019-01-25 | — | — | CN | claimed |
| CN-104497183-A | Method for preparing phthalate imprinted polymer by atom transfer radical polymerization method | UNIV HENAN TECHNOLOGY | 2015-04-08 | — | — | CN | claimed |
| CN-104262306-A | Method for preparing citalopram and S-citalopram | ZHEJIANG HUAHAI PHARM CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-104230836-A | Phenyloxazole compounds and application thereof to preparation of medicament for treating cancers | CHENGDU INST BIOLOGY CAS | 2014-12-24 | — | — | CN | claimed |
| CN-101848891-A | Preparation of synthetic nucleosides by pi-allyl transition metal complex formation | UNIV EMORY | 2010-09-29 | — | — | CN | claimed |
| US-20100204463-A1 | Preparation Of Synthetic Nucleosides via Pi-Allyl Transition Metal Complex Formation | EMORY UNIVERSITY | 2010-08-12 | — | — | US | claimed |
| EP-2185508-A1 | PREPARATION OF SYNTHETIC NUCLEOSIDES VIA pi-ALLYL TRANSITION METAL COMPLEX FORMATION | Emory University (US) | 2010-05-19 | — | — | EP | claimed |
| WO-2009021114-A1 | PREPARATION OF SYNTHETIC NUCLEOSIDES VIA π-ALLYL TRANSITION METAL COMPLEX FORMATION | EMORY UNIVERSITY (US) | 2009-02-12 | — | — | WO | claimed |
| US-6455738-B1 | FRIEDEL-CRAFT CATALYSIS IN THE PRESENCE OF MIXTURES OF LEWIS ACIDS AND SULFONIC ACID ESTERS AS FRIEDEL CRAFT'S CATALYSTS; STOICHIOMETRY | RHODIA CHIMIE (FR) | 2002-09-24 | — | — | US | claimed |
| US-6348631-B1 | REACTING AROMATIC COMPOUND WITH ACYLATING OR SULFONYLATING AGENT IN PRESENCE OF FRIEDEL-CRAFTS CATALYST, WHEREIN ACYLATION OR SULFONYLATION REACTION IS CARRIED OUT IN LIQUID PHASE UNDER MICROWAVE IRRADIATION | RHODIA CHIMIE (FR) | 2002-02-19 | — | — | US | claimed |
| WO-2001068726-A1 | ATOM TRANSFER RADICAL POLYMERISATION CATALYST | BP CHEMICALS LIMITED (GB) | 2001-09-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204463-A1 | Preparation Of Synthetic Nucleosides via Pi-Allyl Transition Metal Complex Formation | PAICS, POLRMT, ZC3HAV1 | HTR6 4491/4885TRPV4 2840/4885NFE2L2 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.