Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889745 | 0.67 | JAK2 (0.38) | LMNAALDH1A1JAK2THRBL3MBTL1 | |
| SCHEMBL17220671 | 0.67 | — | — | |
| SCHEMBL9253625 | 0.64 | NPC1 (0.39) | NPC1 | |
| SCHEMBL11470894 | 0.63 | — | — | |
| SCHEMBL2169311 | 0.62 | DAO (0.41) | — | |
| SCHEMBL4388580 | 0.62 | LMNA (0.31) | LMNAALDH1A1JAK2THRB | |
| SCHEMBL4184455 | 0.62 | APEX1 (0.47) | ALDH1A1HPGD | |
| SCHEMBL9062088 | 0.60 | IDH1 (0.33) | — | |
| SCHEMBL17849940 | 0.60 | JAK2 (0.32) | JAK2THRB | |
| SCHEMBL252499 | 0.60 | JAK2 (0.32) | JAK2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189595-B | Process for preparing urethane-isocyanurates | 陶氏环球技术有限责任公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-107531870-A | The PUR/PIR rigid foams formed by isopropylidenediphenol base polyethers | 科思创德国股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-105829375-A | Allophanate-isocyanurateing catalyst, polyisocyanate composition, method for producing the composition, and two-component coating composition | 东曹株式会社 | 2016-08-03 | — | — | CN | disclosed |
| CN-105189595-A | Process for preparing urethane-isocyanurates | DOW GLOBAL TECHNOLOGIES INC | 2015-12-23 | — | — | CN | disclosed |