SCHEMBL28045461

SCHEMBL28045461

CN(/N=C/c1cccc2ccccc12)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
MAPT P10636 6/20 0.51
TDP1 Q9NUW8 2/20 0.51
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
ALDH1A1 P00352 2/20 0.48
GRIN2D O15399 2/20 0.45
GRIN3B O60391 2/20 0.45
GRIN1 Q05586 2/20 0.45
GRIN2A Q12879 2/20 0.45
GRIN2B Q13224 2/20 0.45
GRIN2C Q14957 2/20 0.45
GRIN3A Q8TCU5 2/20 0.45
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
LMNA P02545 3/20 0.44
HCRTR1 O43613 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702594 1.00 MEN1 (0.51) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL11285503 0.83 POLB (0.51) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL28045547 0.77 MAPT (0.55) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL11282421 0.77 MAPT (0.48) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL28045392 0.76 MAPT (0.54) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL2921333 0.75 ALDH1A1 (0.55) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL1702914 0.75 MAPT (0.65) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL2921336 0.75 ALDH1A1 (0.55) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL14675630 0.75 MAPT (0.53) MEN1KMT2AMAPTTDP1SMN1; SMN2
SCHEMBL14182496 0.74 APP (0.53) MEN1KMT2AMAPTTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105272793-B Method for synthesizing aryl hydrazone 南京理工大学 2017-02-15 CN disclosed
CN-105272793-A Method for synthesizing aryl hydrazone UNIV NANJING SCIENCE & TECH 2016-01-27 CN disclosed