Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 11/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921336 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 | |
| SCHEMBL1702914 | 0.77 | MAPT (0.65) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL1702594 | 0.75 | MEN1 (0.51) | ALDH1A1HPGDCYP1A2HSD17B10MEN1 | |
| SCHEMBL28045461 | 0.75 | MEN1 (0.51) | ALDH1A1HPGDCYP1A2HSD17B10MEN1 | |
| SCHEMBL7384077 | 0.73 | MAPT (0.57) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 | |
| SCHEMBL5289576 | 0.73 | MAPT (0.51) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 | |
| SCHEMBL15841249 | 0.73 | MAPT (0.53) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 | |
| SCHEMBL6096045 | 0.73 | MAPT (0.51) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 | |
| SCHEMBL3652492 | 0.73 | MAPT (0.53) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 | |
| SCHEMBL3652495 | 0.73 | MAPT (0.53) | ALDH1A1HPGDCYP1A2HSD17B10NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1647548-B1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | OREAL (FR) | 2010-08-25 | — | — | EP | disclosed |
| EP-1647548-B1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | OREAL (FR) | 2010-08-25 | — | — | EP | disclosed |
| US-7582122-B2 | Mixed cationic dyes comprising at least one anthraquinone chromophore and their use in methods of hair dyeing | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582122-B2 | Mixed cationic dyes comprising at least one anthraquinone chromophore and their use in methods of hair dyeing | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582122-B2 | Mixed cationic dyes comprising at least one anthraquinone chromophore and their use in methods of hair dyeing | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7569079-B2 | Polycationic monochromophoric hydrazone compounds, dye compositions comprising such polycationic compounds and dyeing process using them | L'OREAL S.A. (FR) | 2009-08-04 | — | — | US | disclosed |
| US-7569079-B2 | Polycationic monochromophoric hydrazone compounds, dye compositions comprising such polycationic compounds and dyeing process using them | L'OREAL S.A. (FR) | 2009-08-04 | — | — | US | disclosed |
| US-20080263785-A1 | Polycationic monochromophoric hydrazone compounds, dye compositions comprising such polycationic compounds and dyeing process using them | L'OREAL S.A. (FR) | 2008-10-30 | — | — | US | disclosed |
| US-20080263785-A1 | Polycationic monochromophoric hydrazone compounds, dye compositions comprising such polycationic compounds and dyeing process using them | L'OREAL S.A. (FR) | 2008-10-30 | — | — | US | disclosed |
| EP-1980558-A1 | Polycationic monochromophoric compounds of hydrazone type, dyeing compositions comprising same and dyeing method | L'Oréal (FR) | 2008-10-15 | — | — | EP | disclosed |
| US-7410506-B2 | Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof | L'OREAL S.A. (FR) | 2008-08-12 | — | — | US | disclosed |
| US-7410506-B2 | Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof | L'OREAL S.A. (FR) | 2008-08-12 | — | — | US | disclosed |
| WO-2007122340-A1 | CATIONIC DICHROMOPHORIC COMPOUND CONTAINING TWO UNITS OF HYDRAZONE TYPE AND COMPRISING A CATIONIC LINKER ARM, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, METHOD FOR THE USE THEREOF AND USES | L'ORÉAL (FR) | 2007-11-01 | — | — | WO | disclosed |
| US-20070125261-A1 | Mixed cationic dyes comprising at least one anthraquinone chromophore and their use in methods of hair dyeing | L'OREAL S.A. (FR) | 2007-06-07 | — | — | US | disclosed |
| US-20070125261-A1 | Mixed cationic dyes comprising at least one anthraquinone chromophore and their use in methods of hair dyeing | L'OREAL S.A. (FR) | 2007-06-07 | — | — | US | disclosed |
| US-20070125261-A1 | Mixed cationic dyes comprising at least one anthraquinone chromophore and their use in methods of hair dyeing | L'OREAL S.A. (FR) | 2007-06-07 | — | — | US | disclosed |
| EP-1757660-A1 | Cationic mixed dyestuffs comprising an anthraquinone chromophore and their use for hair colouring | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
| EP-1757660-A1 | Cationic mixed dyestuffs comprising an anthraquinone chromophore and their use for hair colouring | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
| US-20060096043-A1 | Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof | L'OREAL S.A. (FR) | 2006-05-11 | — | — | US | disclosed |
| EP-1647548-A1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | L'OREAL S.A. (FR) | 2006-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060096043-A1 | Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof | KRT18, DSC1, DSG1 | ALDH1A1 1178/4885HPGD 760/4885CYP1A2 2641/4885 |
| US-20080263785-A1 | Polycationic monochromophoric hydrazone compounds, dye compositions comprising such polycationic compounds and dyeing process using them | KRT18, CKMT1A; CKMT1B, XRCC5 | ALDH1A1 2546/4885HPGD 703/4885CYP1A2 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.