Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419589 | 0.95 | CA2 (0.56) | CA2ACHEAPPCA12CA1 | |
| SCHEMBL20509 | 0.95 | CA2 (0.56) | CA2ACHEAPPCA12CA1 | |
| SCHEMBL1256865 | 0.93 | CA2 (0.54) | CA2ACHEAPPCA12CA1 | |
| Methyl Alcohol SCHEMBL28799088 | 0.91 | CA2 (0.52) | CA2ACHEAPPCA12CA1 | |
| Formaldehyde SCHEMBL23581083 | 0.88 | CA2 (0.50) | CA2ACHEAPPCA12CA1 | |
| SCHEMBL5607372 | 0.83 | CA2 (0.52) | CA2ACHEAPPCA12CA1 | |
| SCHEMBL27601631 | 0.83 | SMN1; SMN2 (0.54) | CA2ACHEAPPCA12CA1 | |
| SCHEMBL22360080 | 0.82 | TDP1 (0.45) | CA2ACHEAPPCA12CA1 | |
| SCHEMBL130149 | 0.81 | APP (0.43) | CA2APPTDP1KDM4EPYCR1 | |
| SCHEMBL4908475 | 0.80 | TDP1 (0.44) | CA2ACHEAPPCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175241-B | Terphenyls compound and its preparation method and application | 浙江工业大学 | 2017-09-29 | — | — | CN | disclosed |
| CN-105175241-A | Terphenyl compound and preparation method therefor and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2015-12-23 | — | — | CN | disclosed |