Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20509 | 0.97 | CA2 (0.56) | CA2ACHECA12CA1CA7 | |
| SCHEMBL29419589 | 0.97 | CA2 (0.56) | CA2ACHECA12CA1CA7 | |
| Ethyne SCHEMBL28045684 | 0.93 | CA2 (0.52) | CA2ACHECA12CA1CA7 | |
| Methyl Alcohol SCHEMBL28799088 | 0.93 | CA2 (0.52) | CA2ACHECA12CA1CA7 | |
| Formaldehyde SCHEMBL23581083 | 0.91 | CA2 (0.50) | CA2ACHECA12CA1CA7 | |
| SCHEMBL5607372 | 0.85 | CA2 (0.52) | CA2ACHECA12CA1CA7 | |
| SCHEMBL27601631 | 0.85 | SMN1; SMN2 (0.54) | CA2ACHECA12CA1CA7 | |
| SCHEMBL22360080 | 0.84 | TDP1 (0.45) | CA2ACHECA12CA1CA7 | |
| SCHEMBL4820063 | 0.83 | HPGD (0.50) | TDP1KDM4EALDH1A1MAPK1TSHR | |
| SCHEMBL4908475 | 0.82 | TDP1 (0.44) | CA2ACHECA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835623-B | New method for synthesizing Almond alkaloid (+/-) membrane | 河北桑迪亚医药技术有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| CN-114835623-A | New method for synthesizing Tetragoniaceae alkaloid (+/-) Mesembrine | 河北桑迪亚医药技术有限责任公司 | 2022-08-02 | — | — | CN | claimed |
| CN-104650059-B | A kind of thiazolone oxime ether derivative and its preparation method and application | 南开大学 | 2018-06-22 | — | — | CN | claimed |
| EP-3805193-B1 | NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF | UNIV EWHA IND COLLABORATION (KR) | 2024-09-11 | — | — | EP | disclosed |
| US-12043594-B2 | Biphenyl derivative compound and use thereof | EWHA University—Industry Collaboration Foundation (KR) | 2024-07-23 | — | — | US | disclosed |
| CN-114835623-B | New method for synthesizing Almond alkaloid (+/-) membrane | 河北桑迪亚医药技术有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-114835623-A | New method for synthesizing Tetragoniaceae alkaloid (+/-) Mesembrine | 河北桑迪亚医药技术有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-08 | — | — | US | disclosed |
| EP-3805193-A1 | NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF | Ewha University-Industry Collaboration Foundation (KR) | 2021-04-14 | — | — | EP | disclosed |
| CN-110317169-A | A kind of 1- substituted isoquinoline ketone compound and preparation method thereof | 复旦大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-104650059-B | A kind of thiazolone oxime ether derivative and its preparation method and application | 南开大学 | 2018-06-22 | — | — | CN | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |
| CN-1066849-A | Three ring triazolo derivatives, its Manufacturing approach and use | TORAY INDUSTRIES (JP) | 1992-12-09 | — | — | CN | disclosed |
| US-4954497-A | AGRICULTURE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4954659-A | FOOD PRESERVATIVE | CHEMEX PHARMACEUTICALS, INC. (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0330939-A2 | Acrylic acid morpholides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0024943-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1983-08-17 | — | — | EP | disclosed |
| US-4387230-A | Process for preparing a dihydropyridine derivative | JOHN WYETH AND BROTHER LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |
| US-4301164-A | FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS | TORAY INDUSTRIES, INC. (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0024943-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1981-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043594-B2 | Biphenyl derivative compound and use thereof | NME4, PCK2, DNAJA3 | CA2 883/4885ACHE 3835/4885CA12 2990/4885 |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | NME4, PCK2, DNAJA3 | CA2 772/4885ACHE 3789/4885CA12 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.