SCHEMBL130149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Ethyne SCHEMBL28045684	0.81	CA2 (0.52)	APPSMN1; SMN2L3MBTL1ALDH1A1KDM4E
	SCHEMBL20509	0.81	CA2 (0.56)	APPSMN1; SMN2L3MBTL1ALDH1A1KDM4E
	SCHEMBL29419589	0.81	CA2 (0.56)	APPSMN1; SMN2L3MBTL1ALDH1A1KDM4E
	SCHEMBL14725300	0.81	TSHR (0.46)	APPAMY1ALMNASMN1; SMN2L3MBTL1
	Formaldehyde SCHEMBL23581083	0.79	CA2 (0.50)	APPSMN1; SMN2ALDH1A1KDM4ETDP1
	SCHEMBL1256865	0.79	CA2 (0.54)	APPSMN1; SMN2L3MBTL1ALDH1A1KDM4E
	SCHEMBL129594	0.78	AMY1A (0.51)	AMY1ALMNASMN1; SMN2L3MBTL1ALDH1A1
	SCHEMBL5832081	0.78	MAPK1 (0.58)	LMNASMN1; SMN2L3MBTL1ALDH1A1TDP1
	Methyl Alcohol SCHEMBL28799088	0.77	CA2 (0.52)	APPSMN1; SMN2L3MBTL1ALDH1A1KDM4E
	SCHEMBL24716965	0.77	NFE2L2 (0.49)	ALDH1A1PPARGPPARDPPARAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.