Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085416 | 0.80 | EPHX1 (0.48) | CTSKCTSLCTSBEPHX1CYP1A2 | |
| SCHEMBL28814855 | 0.72 | MMP2 (0.37) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL12630161 | 0.69 | ACE (0.44) | CTSKCTSLCTSBEPHX1CYP1A2 | |
| SCHEMBL10487993 | 0.68 | CTSK (0.41) | CTSKCTSLCTSBEPHX1CYP1A2 | |
| SCHEMBL232998 | 0.68 | NR1H2 (0.46) | KMT2ATAAR1 | |
| SCHEMBL4715479 | 0.67 | DAO (0.47) | TAAR1 | |
| SCHEMBL9978690 | 0.67 | NR1H2 (0.44) | KMT2ATAAR1 | |
| SCHEMBL11395945 | 0.67 | MDM2 (0.37) | CYP1A2 | |
| SCHEMBL11528941 | 0.67 | CYP1A2 (0.42) | EPHX1CYP1A2TAAR1CPA3FOLH1 | |
| SCHEMBL5173931 | 0.67 | NR1H2 (0.44) | KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121432-A | Heterocyclic amides as kinase inhibitors | GLAXOSMITHKLINE IP DEV LTD | 2015-12-02 | — | — | CN | disclosed |