Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045661 | 0.80 | ALDH1A1 (0.56) | CYP3A4CYP2C19HPGDKDM4EMEN1 | |
| SCHEMBL19246201 | 0.79 | HPGD (0.64) | HTTSMN1; SMN2CYP3A4CYP2C19NPC1 | |
| SCHEMBL2509921 | 0.79 | HTT (0.64) | HTTSMN1; SMN2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL6986059 | 0.79 | HTT (1.00) | HTTSMN1; SMN2POLBHPGDMEN1 | |
| SCHEMBL8567201 | 0.76 | HTT (0.73) | HTTSMN1; SMN2CYP3A4CYP2C19POLB | |
| SCHEMBL9646348 | 0.76 | CTSD (0.63) | HTTSMN1; SMN2CYP3A4CYP2C19NPC1 | |
| SCHEMBL6361089 | 0.74 | SMN1; SMN2 (0.61) | HTTSMN1; SMN2CYP3A4CYP2C19NPC1 | |
| SCHEMBL19246188 | 0.74 | KMT2A (0.75) | HTTCYP3A4CYP2C19GAAHPGD | |
| SCHEMBL30236290 | 0.74 | KMT2A (0.75) | HTTCYP3A4CYP2C19GAAHPGD | |
| SCHEMBL27660006 | 0.74 | HPGD (0.63) | HTTSMN1; SMN2CYP3A4POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198801-A | N-(4-chloro-3-picolyl)-2-(3-methylbenzamide) benzamide as well as preparation method and application thereof | WUHAN INST TECHNOLOGY | 2015-12-30 | — | — | CN | claimed |
| CN-105777713-A | N-(2-pyridyl)-2-(2,4-dimethyl parazole formamido) benzamide as well as preparation thereof and use thereof | 武汉工程大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-105198801-A | N-(4-chloro-3-picolyl)-2-(3-methylbenzamide) benzamide as well as preparation method and application thereof | WUHAN INST TECHNOLOGY | 2015-12-30 | — | — | CN | disclosed |
| CN-105198801-A | N-(4-chloro-3-picolyl)-2-(3-methylbenzamide) benzamide as well as preparation method and application thereof | WUHAN INST TECHNOLOGY | 2015-12-30 | — | — | CN | disclosed |