Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596884 | 1.00 | CTSK (0.55) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL160926 | 1.00 | CTSK (0.55) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL7268311 | 0.83 | KDM1A (0.49) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL7268357 | 0.82 | KDM1A (0.48) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL28288627 | 0.81 | CTSK (0.56) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL26910148 | 0.81 | CTSK (0.56) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL19400126 | 0.81 | CTSK (0.56) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL7160782 | 0.81 | CTSK (0.63) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL27511368 | 0.81 | CTSK (0.63) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL608854 | 0.79 | CTSK (0.72) | CTSKCTSSCTSLCTSBPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641947-A | CD229 CAR T cell and its application method | 犹他大学研究基金会 | 2019-04-16 | — | — | CN | disclosed |
| CN-102724975-B | IRE-1 alpha inhibitors | MANNKIND CORP. (US) | 2015-12-02 | — | — | CN | disclosed |