Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.56 |
| ▸ | CTSL | P07711 | 7/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26910148 | 1.00 | CTSK (0.56) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL28288627 | 1.00 | CTSK (0.56) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL20770089 | 0.86 | CTSK (0.58) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL724546 | 0.85 | CTSK (0.46) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL1014662 | 0.84 | CTSB (0.44) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL17596884 | 0.81 | CTSK (0.55) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL160926 | 0.81 | CTSK (0.55) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL28045793 | 0.81 | CTSK (0.55) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL7160782 | 0.80 | CTSK (0.63) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL27511368 | 0.80 | CTSK (0.63) | CTSKCTSLCTSSCTSBPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210046183-A1 | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF IMMUNE COMPLEX DISEASE | COWAN FRED M (US) | 2021-02-18 | — | — | US | disclosed |
| US-9775842-B2 | Nanocarriers and their processing for diagnostics and therapeutics | RHODE ISLAND HOSPITAL (US) | 2017-10-03 | — | — | US | disclosed |
| CN-102724975-B | IRE-1 alpha inhibitors | MANNKIND CORP. (US) | 2015-12-02 | — | — | CN | disclosed |