Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771303 | 0.86 | ALDH1A1 (0.56) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL12908 | 0.86 | ALDH1A1 (0.56) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL12902 | 0.86 | ALDH1A1 (0.56) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL23394146 | 0.82 | HPGD (0.56) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL8288407 | 0.82 | HPGD (0.56) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL8056889 | 0.77 | RECQL (0.54) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL15107859 | 0.77 | HPGD (0.61) | MEN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL8276848 | 0.77 | RECQL (0.54) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL264879 | 0.77 | RECQL (0.54) | MEN1MAPTKMT2AALDH1A1USP30 | |
| SCHEMBL27480216 | 0.75 | GPR119 (0.45) | MAPTALDH1A1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143222-B | Glycosidase inhibitor | 默克专利有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105143222-A | Glycosidase inhibitors | MERCK PATENT GMBH | 2015-12-09 | — | — | CN | disclosed |