SCHEMBL6164290

SCHEMBL6164290

N#Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRS3 P32247 3/20 0.57
LTB4R2 Q9NPC1 3/20 0.56
HNF4A P41235 1/20 0.49
BCAT2 O15382 1/20 0.47
XDH P47989 2/20 0.46
SLC22A12 Q96S37 2/20 0.46
EIF4E P06730 2/20 0.46
TSHR P16473 1/20 0.45
ALDH1A1 P00352 1/20 0.45
ALOX15 P16050 1/20 0.45
FABP3 P05413 1/20 0.45
FABP4 P15090 1/20 0.45
FABP5 Q01469 1/20 0.45
HTT P42858 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11805019 0.98 BRS3 (0.56) BRS3LTB4R2HNF4ABCAT2XDH
SCHEMBL30292805 0.84 HNF4A (0.63) LTB4R2HNF4ABCAT2ALDH1A1ALOX15
SCHEMBL18759613 0.84 HNF4A (0.63) LTB4R2HNF4ABCAT2ALDH1A1ALOX15
SCHEMBL28045856 0.84 BCAT2 (0.65) BRS3LTB4R2BCAT2TSHRALDH1A1
SCHEMBL15492872 0.84 BRS3 (0.44) BRS3LTB4R2BCAT2TSHRMAOB
SCHEMBL5015475 0.84 LTB4R2 (0.46) BRS3LTB4R2BCAT2ALDH1A1MAOB
SCHEMBL2744720 0.83 TSHR (0.47) BRS3LTB4R2HNF4AXDHSLC22A12
SCHEMBL28622742 0.83 LTB4R2 (0.46) BRS3LTB4R2BCAT2SLC22A12EIF4E
SCHEMBL2744074 0.83 LTB4R2 (0.46) BRS3LTB4R2HNF4AXDHSLC22A12
SCHEMBL2426967 0.83 KAT6A (0.47) BRS3LTB4R2HNF4AXDHSLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4082428-A AROMATIC ESTERS SUNCRUX INCORPORATED (US) 1978-04-04 US claimed
US-4009938-A Liquid crystal display device KABUSHIKI KAISHA SUWA SEIKOSHA (JA) 1977-03-01 US claimed
JP-54101784-A None JP disclosed
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists BAYER AKTIENGESELLSCHAFT (DE) 2025-08-26 US disclosed
EP-4058448-B1 HYDANTOIN DERIVATIVES AS ADAMTS7 ANTAGONISTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES BAYER AG (DE) 2024-05-29 EP disclosed
CN-112236464-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2024-02-23 CN disclosed
CN-112204076-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
CN-113646393-B Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2023-09-19 CN disclosed
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
EP-3822268-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS Bayer Aktiengesellschaft (DE) 2021-05-19 EP disclosed
EP-1254136-A4 FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF LG CHEM INVESTMENT LTD (KR) 2005-06-01 EP disclosed
EP-1254136-A1 FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF LG Chem Investment, Ltd. (KR) 2002-11-06 EP disclosed
WO-2001055146-A1 FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF LG CHEM INVESTMENT LTD. (KR) 2001-08-02 WO disclosed
US-5473068-A Photochromic spirooxazine monomers and polysiloxanes YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) 1995-12-05 US disclosed
US-5322945-A Photochromic spirooxazine monomers and polysiloxanes YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1994-06-21 US disclosed
WO-1993003073-A1 AZO POLYMERS FOR REVERSIBLE OPTICAL STORAGE QUEEN'S UNIVERSITY AT KINGSTON (CA) 1993-02-18 WO disclosed
US-5173381-A Azo polymers for reversible optical storage QUEEN'S UNIVERSITY (CA) 1992-12-22 US disclosed
EP-0167912-B1 LIQUID CRYSTAL MIXTURES CONTAINING COMPOUNDS WITH A 4-ALKENYL OR 2Z-ALKENYL LATERAL CHAIN F. HOFFMANN-LA ROCHE AG (CH) 1990-01-03 EP disclosed
JP-S54101784-A LIQUID CRYSTAL COMPOSITION HITACHI LTD 1979-08-10 JP disclosed
US-4009938-A Liquid crystal display device KABUSHIKI KAISHA SUWA SEIKOSHA (JA) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists ADAMTS7, MMP7, ADAM17 BRS3 160/4885LTB4R2 1814/4885HNF4A 3017/4885
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAM17 BRS3 160/4885LTB4R2 1814/4885HNF4A 3017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.