Methylamine

Methylamine

SCHEMBL28045975

CN.Cc1ccc(Cl)c(Cl)c1C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.41
ALDH1A1 P00352 3/20 0.36
HTR2B P41595 2/20 0.35
MAPK1 P28482 1/20 0.35
CHRM1 P11229 1/20 0.35
ALOX15 P16050 1/20 0.35
MAOA P21397 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
CD44 P16070 1/20 0.33
PLA2G7 Q13093 1/20 0.32
CES1 P23141 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258271 0.95 CYP3A4 (0.39) CYP3A4ALDH1A1HTR2BMAPK1CHRM1
SCHEMBL27803122 0.95 CYP3A4 (0.39) CYP3A4ALDH1A1HTR2BMAPK1CHRM1
SCHEMBL10583579 0.87 CYP3A4 (0.34) CYP3A4ALDH1A1HTR2BMAPK1CHRM1
SCHEMBL13176835 0.78 CYP3A4 (0.44) CYP3A4ALDH1A1HTR2BMAPK1LMNA
SCHEMBL6441444 0.77 CYP3A4 (0.41) CYP3A4ALDH1A1HTR2BCHRM1ALOX15
SCHEMBL900037 0.77 ALDH1A1 (0.42) CYP3A4ALDH1A1HTR2BMAPK1HTR2A
Butyl Chloride SCHEMBL28975559 0.77 TSHR (0.42) ALDH1A1LMNACYP1A2PNMTTSHR
SCHEMBL180306 0.75 CYP3A4 (0.46) CYP3A4ALDH1A1HTR2BMAPK1CHRM1
SCHEMBL5734545 0.75 CYP3A4 (0.40) CYP3A4ALDH1A1POLBLMNACD44
SCHEMBL29370015 0.75 CYP3A4 (0.46) CYP3A4ALDH1A1HTR2BMAPK1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315160-A Benzyl tertiary amine, preparation method and applications thereof UNIV ZHEJIANG OCEAN 2016-02-10 CN disclosed