Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3875612 | 0.97 | CYP3A4 (0.39) | CYP3A4ALDH1A1MAPTCES1CYP1A2 | |
| SCHEMBL6681654 | 0.87 | ALDH1A1 (0.48) | CYP3A4ALDH1A1MAPTCES1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL309539 | 0.83 | ALDH1A1 (0.46) | CYP3A4ALDH1A1MAPTCES1CYP1A2 | |
| SCHEMBL5494672 | 0.79 | TSHR (0.45) | CYP3A4ALDH1A1MAPTCYP1A2CYP2A6 | |
| SCHEMBL29352563 | 0.79 | TSHR (0.45) | CYP3A4ALDH1A1MAPTCYP1A2CYP2A6 | |
| SCHEMBL37955 | 0.79 | TSHR (0.45) | CYP3A4ALDH1A1MAPTCYP1A2CYP2A6 | |
| SCHEMBL3239977 | 0.79 | ALDH1A1 (0.39) | CYP3A4ALDH1A1MAPTCES1RAPGEF4 | |
| SCHEMBL258271 | 0.79 | CYP3A4 (0.39) | CYP3A4ALDH1A1MAPTCES1CYP1A2 | |
| SCHEMBL10346182 | 0.75 | TSHR (0.43) | CYP3A4ALDH1A1MAPTCYP1A2CYP2A6 | |
| Bromide SCHEMBL29115028 | 0.75 | TSHR (0.43) | CYP3A4ALDH1A1MAPTCYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101279998-B | Preparation of C-terminal ethylamine polypeptides and derivates thereof | GL BIOCHEM SHANGHAI LTD | 2011-07-06 | — | — | CN | claimed |
| US-5159082-A | Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound | MITSUBISHI KASEI CORPORATION (JP) | 1992-10-27 | — | — | US | claimed |
| EP-0405389-A1 | Process for producing an aromatic compound | Mitsubishi Chemical Corporation (JP) | 1991-01-02 | — | — | EP | claimed |
| US-4140695-A | Process for producing copper phthalocyanines | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1979-02-20 | — | — | US | claimed |
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| EP-3507275-B1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| CN-114284439-A | Method for preparing CsPbI3 perovskite thin film and high-efficiency solar cell thereof in high-humidity environment and application | 南京工业大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-106536528-B | Polycyclic polymers based on tetra-heteroaryl indacenodithiophenes and their use | 默克专利股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| US-11040954-B1 | CXCR3 receptor agonists | RECEPTOS LLC (US) | 2021-06-22 | — | — | US | disclosed |
| US-10889593-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2021-01-12 | — | — | US | disclosed |
| CN-107636040-B | Thiadiazolopyridine polymers, their synthesis and their use | 默克专利股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111315797-A | Organic semiconductor compound | 默克专利股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| WO-2004085403-A1 | TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-10-07 | — | — | WO | disclosed |
| US-20040156904-A1 | Biodegradable polymer device | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2004-08-12 | — | — | US | disclosed |
| EP-0405389-B1 | Process for producing an aromatic compound | MITSUBISHI CHEM IND (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5159082-A | Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound | MITSUBISHI KASEI CORPORATION (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0405389-A1 | Process for producing an aromatic compound | Mitsubishi Chemical Corporation (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0188394-B1 | PROCESS FOR PURIFYING AN AQUEOUS SOLUTION OF RARE-EARTH SALT BY LIQUID-LIQUID EXTRACTION | RHONE-POULENC CHIMIE (FR) | 1988-06-01 | — | — | EP | disclosed |
| EP-0188394-A1 | Process for purifying an aqueous solution of rare-earth salt by liquid-liquid extraction | RHONE-POULENC CHIMIE (FR) | 1986-07-23 | — | — | EP | disclosed |
| US-4140695-A | Process for producing copper phthalocyanines | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1979-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | TLR7, TLR8, TLR9 | CYP3A4 3093/4885ALDH1A1 2648/4885MAPT 4219/4885 |
| US-11040954-B1 | CXCR3 receptor agonists | CXCR3, CXCR1, CCR7 | CYP3A4 1911/4885ALDH1A1 1802/4885MAPT 4432/4885 |
| US-10889593-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | CKS1B, IKZF3, EPAS1 | CYP3A4 3800/4885ALDH1A1 2758/4885MAPT 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.