Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17674529 | 0.84 | KMT2A (0.45) | L3MBTL1FPR2 | |
| SCHEMBL28042117 | 0.84 | EGFR (0.39) | OPRM1DPP8DPP9 | |
| SCHEMBL27788488 | 0.79 | KMT2A (0.43) | OPRM1L3MBTL1FPR2 | |
| SCHEMBL27878075 | 0.79 | POLB (0.36) | L3MBTL1ACHEBCHEDPP8DPP9 | |
| SCHEMBL28807673 | 0.79 | HSD11B1 (0.43) | — | |
| SCHEMBL17674500 | 0.79 | APP (0.40) | OPRM1 | |
| SCHEMBL27869042 | 0.79 | GAA (0.32) | — | |
| SCHEMBL5644519 | 0.78 | OPRM1 (0.39) | OPRM1CA1CA2 | |
| SCHEMBL22657406 | 0.76 | AAK1 (0.43) | CA1CA2 | |
| SCHEMBL22657411 | 0.76 | P2RX7 (0.35) | OPRM1ACHEBCHEFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531264-B | Antibacterial 2H-indazole derivatives | 爱杜西亚药品有限公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-105531264-A | Antibacterial 2H-indazole derivatives | ACTELION PHARMACEUTICALS LTD | 2016-04-27 | — | — | CN | disclosed |