Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824869 | 0.79 | S1PR1 (0.39) | S1PR1TP53LMNAJAK2ALDH1A1 | |
| SCHEMBL31217358 | 0.71 | GBA1 (0.56) | S1PR1TP53LMNAJAK2ALDH1A1 | |
| SCHEMBL16115369 | 0.68 | TP53 (0.39) | S1PR1TP53LMNAJAK2ALDH1A1 | |
| SCHEMBL16114911 | 0.68 | TP53 (0.38) | S1PR1TP53LMNAJAK2ALDH1A1 | |
| SCHEMBL27837312 | 0.66 | TP53 (0.40) | S1PR1TP53LMNAJAK2ALDH1A1 | |
| SCHEMBL28291417 | 0.66 | S1PR1 (0.37) | S1PR1TP53LMNAALDH1A1KDM4E | |
| SCHEMBL4474636 | 0.65 | ADH1C (0.41) | S1PR1TP53ADH1CADH1A | |
| SCHEMBL4484272 | 0.65 | ADH1C (0.41) | S1PR1TP53ADH1CADH1A | |
| SCHEMBL7811855 | 0.65 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL20797487 | 0.65 | ALDH1A1 (0.40) | S1PR1TP53LMNAJAK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102454-A | Novel oxazolidinone derivative as cetp inhibitor, its preparation method, and pharmaceutical composition comprising the same | DONG A ST CO LTD | 2015-11-25 | — | — | CN | disclosed |