Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046306 | 0.79 | S1PR1 (0.38) | S1PR1TP53LMNAJAK3JAK2 | |
| SCHEMBL31217358 | 0.78 | GBA1 (0.56) | S1PR1HRH3HRH4TP53LMNA | |
| SCHEMBL20797487 | 0.72 | ALDH1A1 (0.40) | S1PR1TP53LMNAJAK3JAK2 | |
| SCHEMBL17232494 | 0.70 | LMNA (0.45) | HRH3HRH4TP53LMNAJAK3 | |
| SCHEMBL7993536 | 0.69 | HDAC6 (0.40) | AOC3 | |
| SCHEMBL3059414 | 0.69 | AURKA (0.48) | HRH3LMNALCKSMN1; SMN2ALDH1A1 | |
| SCHEMBL9537873 | 0.69 | S1PR1 (0.43) | S1PR1LMNAMEN1KMT2A | |
| SCHEMBL22920033 | 0.67 | CYP19A1 (0.39) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4484272 | 0.67 | ADH1C (0.41) | S1PR1HRH3HRH4TP53MEN1 | |
| SCHEMBL4474636 | 0.67 | ADH1C (0.41) | S1PR1HRH3HRH4TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102454-A | Novel oxazolidinone derivative as cetp inhibitor, its preparation method, and pharmaceutical composition comprising the same | DONG A ST CO LTD | 2015-11-25 | — | — | CN | disclosed |