Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219895 | 0.90 | RXRA (0.46) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL4394385 | 0.84 | SLC22A12 (0.36) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL29431092 | 0.84 | SLC22A12 (0.36) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL31037153 | 0.82 | SLC22A12 (0.35) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL30130262 | 0.78 | MRGPRX4 (0.36) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL29115260 | 0.78 | SLC22A12 (0.36) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL30839044 | 0.78 | SLC22A12 (0.36) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL31037149 | 0.76 | METAP2 (0.39) | RXRARXRBRXRGMRGPRX4SLC22A12 | |
| SCHEMBL16232103 | 0.75 | MAPT (0.55) | RXRARXRBRXRG | |
| SCHEMBL2608851 | 0.75 | RXRA (0.45) | RXRARXRBRXRGMRGPRX4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294515-A | Preparation method of 2-(2',2'-difluoroethoxy)-6-(trifluoromethyl)benzene-1-sulfonyl chloride | TIANJIN MODERN VOCATIONAL TECHNOLOGY COLLEGE | 2016-02-03 | — | — | CN | claimed |
| CN-109803970-A | New model, the Its Preparation Method And Use of penoxsuam | 江苏龙灯化学有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-104557800-B | 2-phenoxyl tetrahydrofuran (tetrahydropyrane) derivatives and application thereof in synthesis of penoxsulam | 常州大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-105294515-A | Preparation method of 2-(2',2'-difluoroethoxy)-6-(trifluoromethyl)benzene-1-sulfonyl chloride | TIANJIN MODERN VOCATIONAL TECHNOLOGY COLLEGE | 2016-02-03 | — | — | CN | disclosed |