Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431092 | 1.00 | SLC22A12 (0.36) | SLC22A12MRGPRX4PPARGRXRARXRB | |
| SCHEMBL31037153 | 0.99 | SLC22A12 (0.35) | SLC22A12MRGPRX4PPARGRXRARXRB | |
| SCHEMBL30130262 | 0.86 | MRGPRX4 (0.36) | SLC22A12MRGPRX4PPARGRXRARXRB | |
| SCHEMBL29115260 | 0.86 | SLC22A12 (0.36) | SLC22A12MRGPRX4PPARGRXRARXRB | |
| SCHEMBL30839044 | 0.86 | SLC22A12 (0.36) | SLC22A12MRGPRX4PPARGRXRARXRB | |
| SCHEMBL28046559 | 0.84 | RXRA (0.43) | SLC22A12MRGPRX4PPARGRXRARXRB | |
| SCHEMBL8764071 | 0.82 | KCNK3 (0.44) | MRGPRX4RXRARXRBRXRGKCNK3 | |
| SCHEMBL26135789 | 0.81 | SLC22A12 (0.50) | SLC22A12MRGPRX4PPARGSCN5ASCN9A | |
| SCHEMBL6676444 | 0.80 | PIM1 (0.39) | SLC22A12MRGPRX4RXRARXRBRXRG | |
| SCHEMBL28771004 | 0.79 | SLC22A12 (0.38) | SLC22A12MRGPRX4PPARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703726-B | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115974729-B | Preparation method of 2- (2, 2-difluoroethoxy) -6-trifluoromethyl benzenesulfonyl chloride | 营口昌成新材料科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117327076-A | Synthesis method of penoxsulam | 湖北广富林生物制剂有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-115974729-A | Preparation method of 2- (2,2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 营口昌成新材料科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-114539103-B | Synthesis method of 2-difluoroethoxy-6-trifluoromethylbenzenesulfonyl chloride | 佳木斯黑龙农药有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115703726-A | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-115340479-A | Synthetic method of 2- (2,2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 山东华升新材料有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-216919074-U | 2- (2,2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride production system | 内蒙古蓝科生物科技有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114539103-A | Synthesis method of 2-difluoroethoxy-6-trifluoromethylbenzenesulfonyl chloride | 佳木斯黑龙农药有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-112939818-B | Synthetic method of 2- (2, 2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 江苏扬农化工股份有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-111662217-B | Compound with weeding performance and containing hexafluorosulfonamide structure and synthesis method thereof | 江苏富鼎化学有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-110698363-B | Synthetic method of 2- (2, 2-difluoroethoxy) -6- (trifluoromethyl) benzenesulfonyl chloride | 杭州师范大学 | 2022-02-01 | — | — | CN | claimed |
| CN-113045502-A | Compound and synthesis method and application thereof | 江苏富鼎化学有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-112939818-A | Synthetic method of 2- (2, 2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 江苏扬农化工股份有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-111662217-A | Compound with weeding performance and containing hexafluorosulfonamide structure and synthesis method thereof | 江苏富鼎化学有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-110698363-A | Synthetic method of 2- (2, 2-difluoroethoxy) -6- (trifluoromethyl) benzenesulfonyl chloride | 杭州师范大学 | 2020-01-17 | — | — | CN | claimed |
| CN-103880727-B | A kind of halo sulphur compound and its preparation method and application | LUZHOU DONGFANG AGROCHEMICAL CO., LTD. (CN) | 2016-01-13 | — | — | CN | claimed |
| CN-103880727-A | Halogenated sulfur compound and preparation method and application thereof | LUZHOU ORIENTAL AGROCHEMICALS CO LTD | 2014-06-25 | — | — | CN | claimed |
| CN-117865771-A | Synthesis method of 2, 3-dichloro benzotrifluoride | 上海泰初化工技术有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20050215570-A1 | Process for the preparation of N-([1,2,4]triazolopyrimidin-2-yl)aryl sulfonamides | CORTEVA AGRISCIENCE LLC | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215570-A1 | Process for the preparation of N-([1,2,4]triazolopyrimidin-2-yl)aryl sulfonamides | NISCH, CLIC4, CLIC1 | SLC22A12 4186/4885MRGPRX4 1935/4885PPARG 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.