SCHEMBL28046675

SCHEMBL28046675

c1cnc(SOSc2cnccn2)cn1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.39
KDM4E B2RXH2 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
BAZ2B Q9UIF8 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
TSHR P16473 1/20 0.32
MC4R P32245 1/20 0.32
ADRA1A P35348 1/20 0.32
MC3R P41968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211340 0.76 LMNA (0.45) LMNAHSP90AA1KDM4ENAPRTHCAR2
SCHEMBL15516303 0.76 LMNA (0.45) LMNAHSP90AA1KDM4ENAPRTHCAR2
SCHEMBL8083497 0.72
SCHEMBL28006477 0.72
SCHEMBL1617422 0.72
SCHEMBL9252715 0.72
SCHEMBL22327277 0.68
SCHEMBL6851940 0.67
SCHEMBL9018811 0.67 LMNA (0.52) LMNAHSP90AA1KDM4ENAPRTHCAR2
SCHEMBL1475095 0.67 LMNA (0.43) LMNAHSP90AA1KDM4ENAPRTHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105218418-A A kind of preparation method of thioether UNIV YICHUN 2016-01-06 CN disclosed