⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211340 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL15516303 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL8083497 | 0.69 | — | — | |
| SCHEMBL1617422 | 0.69 | — | — | |
| SCHEMBL28006477 | 0.69 | — | — | |
| SCHEMBL9252715 | 0.69 | — | — | |
| SCHEMBL4837646 | 0.68 | — | — | |
| SCHEMBL28046675 | 0.67 | LMNA (0.41) | — | |
| SCHEMBL1479730 | 0.67 | LMNA (0.55) | — | |
| SCHEMBL10873549 | 0.65 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |